Discover how five distinct immune markers reveal the full picture of food reactivity, gut barrier health, and chronic inflammation driving today’s most common metabolic conditions.
Most food sensitivity panels only test IgG. The EAT144 test measures all five immune pathways — giving practitioners and patients a complete, accurate picture of how the immune system is responding to food.
Immediate hypersensitivity. Drives mast cell activation, histamine release, and anaphylactic risk.
Blocks IgE reactions — but chronically elevated IgG4 increases autoimmune risk over time.
Reactions appear up to 72 hours after eating. A major driver of low-grade systemic inflammation.
Activates independently — then intensifies IgG responses and drives pro-allergenic TH2 immunity.
High IgA signals active gut inflammation. Low IgA means the barrier is depleted and defenseless.
Most panels cover ~88 foods. EAT144 tests 144 — giving patients a broader green-light list and fewer dietary restrictions.
How lipopolysaccharide (LPS) from a broken gut barrier drives insulin resistance, brain inflammation, and thyroid dysfunction
The gut-heart axis — TMAO, short-chain fatty acids, and why low butyrate accelerates atherosclerosis
IgG food antibodies in obese children linked to increased carotid intimal thickness and atherosclerosis risk
Clinical trial data: IgG elimination diets outperformed calorie restriction for weight loss, BMI, and fasting glucose
How stress, cortisol, and sympathetic dominance break down the gut mucosal barrier via IL-6 and claudin-2
Mood disorders, neuroinflammation, and the downstream effects of IgG antibodies and C3 epitopes on neurotransmitter metabolism
Academic Co-Chair, American Academy of Anti-Aging Medicine · Chief Science Officer, Lifetime · Founder, Metabolic Code Enterprises · Chair, International Peptide Society. Jim has practiced functional and metabolic medicine since 1990, pioneering integrative approaches to food sensitivity, cardiometabolic health, and longevity.
"The one thing that people need to do every day is eat. And if you're eating foods on a regular basis that are triggering inflammatory signaling, you're pushing down this funnel towards cellular, mitochondrial disruption."
Built for Practitioners and Informed Patients
Watch the webinar, then explore the EAT144 test — 144 foods, five immune pathways, one clear map.
Watch the webinar, then explore the EAT144 test — 144 foods, five immune pathways, one clear map.
Free Practitioner Resource Microbiome, Food Sensitivities & Inflammation: A Clinical eBook for Practitioners Understand the immunological mechanisms driving chronic disease — and how advanced food
Health & Wellness Understanding Your Food Sensitivities and Allergies Discover the Root of Your Symptoms with EAT144 144 Antigens Tested Foods, Chemicals & Environmental Triggers
On-Demand webinar Gut-Inflammation, Allergies, and Metabolic Health Masterclass So today we’re gonna talk about the links between food allergies and sensitivities and weight gain along
On-Demand Webinar How to Order Test Kits Through the EAT144 Portal Ordering the EAT144 test for your patients has never been easier. Watch this quick
